Sun Devils beat Tigers in overtime
Arizona State (2-0), playing in front of a "Black Out" crowd at Sun Devil Stadium, built a 30-16 lead behind Osweiler's 353 yards and three touchdowns passing, and another score rushing.
Missouri (1-1) charged back in the fourth quarter behind James Franklin, who hit L'Damian Washington on a 25-yard touchdown pass and tied it on 3-yard TD pass to Michael Egnew with 2:50 left.
Missouri's Grant Ressel missed a 48-yard field goal with 12 seconds left in regulation, then Osweiler opened overtime with the TD pass to Miles, his second of the game.
Missouri's final chance ended when Franklin's pass on fourth down fell harmlessly in the end zone, ending a back-and-forth game that included 23 penalties for 224 yards.
Aaron Pflugrad had eight catches for 180 yards and a pair of touchdowns-- the second on a trick play from Miles--and Arizona State had 492 yards to end a 10-game losing streak against ranked opponents.
Franklin threw for 319 yards and two touchdowns, and ran for 84 yards and another score. Missouri had 501 total yards, but converted just three of 15 third-down chances to see its 22-game winning streak in regular-season non-conference games come to an end.
Both teams came in looking to make a statement against a big-time program after opening against smaller schools.
Arizona State rolled over UC Davis in its opener, thanks to 262 yards and a pair of touchdowns from Osweiler, along with a stingy defense that held the FCS Aggies to minus-4 yards rushing before giving up a couple of late scores.
This matchup had Sun Devil Stadium juiced in a sellout crowd, which was the first since 2008. 70,236 fans dressed in black to create the "Black Out." A nearby lightning storm added to the buzz, as did the celebrities in attendance: golfer Phil Mickelson, Arizona Cardinals receiver Larry Fitzgerald and Phoenix Suns guard Steve Nash, not to mention a dozen or so NFL scouts.
They got to see quite a show.
Osweiler was sharp from the opening drive, squeezing a 12-yard touchdown pass between two defenders to Miles, who was pinballed but still held on.
Alex Garoutte's 47-yard field goal after a fourth-down conversion was wiped out by a penalty early in the second quarter, but Osweiler answered Missouri's first touchdown with a 60-yard scoring pass to Pflugrad on the next play.
Osweiler had the hockey assist on back pass to Miles, who hit Pflugrad for a 35-yard touchdown pass, then took it in himself for a rumbling 12-yard touchdown run up the middle that put ASU up 30-16. Osweiler finished 24-for-32.
Franklin followed with the 3-yard touchdown pass to Egnew, tying it at 30-all with 2:50 left, and had the Tigers moving again, but Ressel missed the final chance in regulation. Franklin's last-ditch attempt on fourth down in overtime fell in the corner of the endzone when he receiver cut inside. He finished 26 for 42.