Scientist calls for new approach to biomarker research

In an invited commentary published in the Jan. 13 issue of Nature, George Poste, chief scientist for ASU’s Complex Adaptive Systems Initiative, makes a case for replacing the current patchwork of fragmented research on disease-associated biomarkers with a coordinated "big science" approach. Biomarkers are molecular changes in body tissues and fluids that signal the presence of a disease.

Poste argues that biomarkers have the potential to dramatically improve the ability of physicians to diagnose disease and tailor treatments to individuals, but that current research is not delivering on this potential. He outlines key changes needed to advance this important area of medical research.

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For more information about Poste, chief scientist for ASU’s Complex Adaptive Systems Initiative, visit http://casi.asu.edu/.